CLINICAL TRIALS
Advancing 8R‑70CAR T Cell Therapy Through Clinical Trials
Our clinical-stage 8R‑70CAR program is being evaluated across adult and pediatric brain tumors, establishing a foundation for potential development in additional solid and liquid tumors
Explore the Studies Clinical Development Programs
8R‑70CAR is being evaluated in three Phase I clinical programs spanning adult glioblastoma, pediatric high-grade glioma and DIPG, and brain metastases.
IMPACT
Adult Glioblastoma
Phase I • NCT05353530
A Phase I study evaluating the safety, feasibility, cellular kinetics, and preliminary activity of intravenously administered 8R‑70CAR T cells in adults with newly diagnosed glioblastoma.
View Study →pIMPACT
Pediatric High-Grade Glioma
Phase I • NCT06946680
A Phase I study evaluating the safety, feasibility, cellular kinetics, and preliminary activity of 8R‑70CAR T cells in children and adolescents with high-grade glioma, including DIPG.
View Study →IMPACT-MET
Brain Metastases
Phase I • NCT07569263
A Phase I study evaluating the safety, feasibility, cellular kinetics, and preliminary activity of intravenously administered 8R‑70CAR T cells in adults with brain metastases.
View Study →8R-70CAR T Cell Treatment Journey
